A clinical trial is a research study to answer specific questions about new therapies, or new ways of using known treatments. Clinical trials determine if the new drugs or treatments are both safe and effective.

BioCryst's current studies are listed below. Talk with your doctor to determine if participating in a clinical trial is right for you. For more information on clinical trials being conducted by BioCryst please click on the links below or email clinicaltrials@biocryst.com.

For general information on clinical trials please visit http://www.clinicaltrials.gov.

Peramivir

At this time, peramivir is available in the U.S. only through participation in the ongoing Phase 3 studies. You can find details regarding these studies on the web at clinicaltrials.gov by following the links below. If you require more information about access to peramivir than is currently available on these websites, please call 1-205-989-3262.

• A Phase III Study to Evaluate the Efficacy and Safety of IV Peramivir in Addition to Standard of Care Compared to Standard of Care Alone in Adults and Adolescents Who Are Hospitalized Due to Influenza

BCX4208

• A Phase II Study to Evaluate sUA Lowering Activity, Safety and Efficacy of Oral BCX4208 Added to Allopurinol
• A Phase II Randomized, Double-Blind, Dose-Response Study of the Safety and Uric Acid Effects of Oral BCX4208 Added to Allopurinol in Subjects with Gout and Concomitant Moderate Renal Insufficiency